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DNA Repair Proteins, EnzymesEndonuclease III (Nth)
Endonuclease III (Nth) protein from E. coli acts as both N-glycosylase and a AP-lyase. The N-glycosylase activity releases damaged pyrimidines from double-stranded DNA, generating a basic (AP site).
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DNA Repair Proteins, EnzymesEndonuclease IV, E. coli
A class II apurinic/apyrimidic (AP) enzyme that cleaves 5’ to an AP site by hydrolysis leaving a hydroxyl group at the 3´ terminus and a deoxyribose 5´-phosphate at the 5´…
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DNA Repair Proteins, Enzymes
Endonuclease V, E. coli
Endonuclease V, (Endo V) is a 3′-endonuclease involved in DNA repair, which initiates removal of deaminated bases from damaged DNA, including uracil, hypoxanthine, and xanthine.
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DNA Repair Proteins, Enzymes
Endonuclease VIII, E. coli
Endonuclease VIII from E. coli acts as both an N-glycosylase and an AP-lyase. The N-glycosylase activity releases damaged pyrimidines from double-stranded DNA, generating an apurinic (AP site).
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Magnetic Beads, Nucleic Acid Purification
Epoxy Magnetic Beads
Puramag™ superparamagnetic beads are versatile tools for convenient and effective isolation of various biomolecules.
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Protein Purification, Protein Purification Resins
Epoxy-activated Agarose for Ligand or Protein Coupling
Epoxy-activated Agarose is a pre-activated affinity chromatography support for the immobilization of a variety of biomolecules that contain nucleophiles, such as hydroxyl, amino, or thiol groups. These groups couple to…
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Accessories and Reagents, Sanger Sequencing & Fragment AnalysisExo-Resistant Random Hexamer
Protects from 3’=>5′ exonuclease degradation and ensures efficient priming of DNA synthesis.
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NGS Services, Services
Exome Sequencing
The exome represents less than 2% of the human genome, but contains ~85% of known disease-causing variants, making whole-exome sequencing a cost-effective alternative to whole-genome sequencing. With exome sequencing, you…
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Enzymes, NucleasesExonuclease I (E. coli)
Exonuclease I cleaves single-stranded DNA in the 3′→ 5′ direction, releasing 5′ -mono/di-nucleotides and leaving double-stranded DNA molecules and the 5′-terminus intact.
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Enzymes, NucleasesExonuclease III (E. coli)
Exonuclease III is a 3′→ 5′ exonuclease which acts by digesting one strand of a dsDNA duplex at a time or digesting the RNA strand of an RNA-DNA heteroduplex (1).
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Enzymes, Nucleases
Exonuclease VII
Exonuclease VII, (Exo VII) derived from E. coli, cleaves single-stranded DNA (ssDNA) from both 5´→3´ and 3´→5´ directions.
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Enzymes, Single-Stranded DNA Binding Proteins
Extreme Thermostable SSB (ET SSB)
Extreme Thermostable SSB is a single-stranded DNA binding protein isolated from a hyperthermophilic microorganism, which remains fully active after incubation at 95°C for 60 minutes.
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