Recombinant Human BDNF
$0.00 – $113.00
Human Brain-Derived Neurotrophic Factor (BDNF) is a member of the Nerve growth factor family. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems.
| SKU | OPTIONS | Price | Quantity | ||
|---|---|---|---|---|---|
| BDNF-100 | Brain-Derived Neurotrophic Factor (100 ug,1 mg/ml) | $45.00 | |||
| BDNF -200 | Brain-Derived Neurotrophic Factor (0.5 mg,1 mg/ml) | $113.00 | |||
| BDNF -OEM | Brain-Derived Neurotrophic Factor (Any size) | Please inquire |
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Description
Description:
Human Brain-Derived Neurotrophic Factor (BDNF) is a member of the Nerve growth factor family. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. During development, BDNF promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. It participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. It functions as the major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability.
Full Name:
Human Brain-Derived Neurotrophic Factor
Source:
E. coli
Species:
Human
Accession #:
P23560
Molecule Weight:
The mature recombinant human BDNF consists of 119 amino acids (129-247) and has a predicted molecular mass of 27 kDa. BDNF exists as a homodimer in solution.
Purity:
> 95 % as determined by SDS-PAGE
Endotoxin:
< 1.0 EU per μg of the protein as determined by the LAL method
Activity:
ED50 = 1 – 3 µg/mL as measured by the ability of the protein to induce the proliferation of C6 glioma cells.
Storage:
-80 Avoid repeated freeze-thaw cycles.
Storage Buffer:
PBS
Additional information
| OPTIONS | Brain-Derived Neurotrophic Factor (100 ug,1 mg/ml), Brain-Derived Neurotrophic Factor (0.5 mg,1 mg/ml), Brain-Derived Neurotrophic Factor (Any size) |
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